|
KMID : 0604520130390010001
|
|
Journal of the Society of Cosmetic Scientists of Korea
2013 Volume.39 No. 1 p.1 ~ p.8
|
|
|
Comparative Study on Antioxidative Activity of Glycyrrhiza uralensis and Glycyrrhiza glabra Extracts by Country of Origin
|
|
Han Seat-Byeol
Gu Hyun-A
Kim Su-Ji
Kim Hye-Jin
Kwon Soon-Sik
Kim Hae-Soo
Jeon So-Ha
Hwang Jun-Pil
Park Soo-Nam
|
|
|
Abstract
|
|
|
|
In this work, comparative study on antioxidative activities of extracts from Glycyrrhiza uralensis (G. uralensis) produced in Korea and in China and Glycyrrhiza glabra (G. glabra) produced in Uzbekistan was conducted. Among three origins, 50% ethanol extracts (21.15 μg/mL), ethyl acetate fraction (29.15 μg/mL) and aglycone fraction (3.26 μg/mL) of G. uralensis from Korea showed the higher free radical (1,1-phenyl-2-picrylhydrazyl, DPPH) scavenging activity (FSC50) than extracts from other origins. Reactive oxygen species (ROS) scavenging activities (OSC50) of extracts from three origins on ROS generated in Fe3+-EDTA/H2O2 system were investigated using luminol-dependent chemiluminescence assay 50% ethanol extract (1.00 μg/mL) and ethyl acetate fraction (0.34 μg/mL) of G. uralensis from China showed the most prominent ROS scavenging activity. The protective effects of extract/fractions of G. uralensis and G. glabra extracts on the rose-bengal sensitized photohemolysis of human erythrocytes were investigated. 50% ethanol extract and aglycone fraction of G. uralensis and G. glabra extracts from three origins showed cellular protective effects in a concentration dependent manner (5 ∼ 50 μg/mL). Aglycone fraction of G. uralensis from Korea (τ50 = 847.4min)especially showed cellular protective effects four times higher than that from China (τ50 = 194.3 min). These results indicate that G. uralensis and G. glabra extracts, which have been used as whitening agent, could be applicable to functional cosmetic ingredient as a natural antioxidant. Judging from the prominent cellular protecitve effects, it is concluded that G. uralensis and G. glabra extracts can protect the skin from 1O2 and various ROS induced by UV.
|
|
|
KEYWORD
|
|
|
Glycyrrhiza uralensis, Glycyrrhiza glabra, photoaging, antioxidative activity, cellular protective effect
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|